Research

The Yamamoto Lab works on diverse research topics using Drosophila

Most of our projects are related to the nervous system

We collaborate with diverse clinical groups to discover novel genes and variants that cause rare human diseases

We are identifying new genes that regulate the level of dopamine in the brain

We are investigating the function of a novel late-onset Alzheimer's disease risk gene and its close relatives

We performed a large chemical mutagenesis screen on the fly X-chromosome to identify genes that play essential roles

We are studying the functional consequences of rare genetic variants seen in individuals with autism spectrum disorders

We are studying Zika virus related neurological diseases and COVID-19 using fruit flies

We are developing novel tools that facilitates collaborations between basic scientists and clinical researchers