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  • Writer's pictureShinya Yamamoto

Review: How we were able to identify many genes involved in neurodegeneration using fruit flies

Updated: Aug 7, 2022

This review summarizes the outcome of a large forward genetic screen that I initiated when I was still a PhD student in Dr. Hugo Bellen's lab. Here, we are specifically focused on genes that cause neurodegeneration when mutated, and discuss how mutations in these genes have provided new mechanistic insights into how neuronal health and integrity are maintained.



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