News & Updates

News and updates from the Yamamoto lab

Review: Model organisms facilitate rare disease diagnosis and therapeutic research

We wrote a focused review article that discusses how model organism research facilitates both diagnosis of rare human diseases and...

MARRVEL: A powerful search engine to gather genetic information from humans and model organisms

In collaboration with bioinformaticians and programmers in Dr. Zhandong Liu's lab, we developed MARRVEL (Model organism Aggregated...

A new genetic risk factor for late-onset Alzheimer's disease has been identified

Through a large population genomics study conducted by the CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology)...

Review: Morgans legacy -fruit flies and the functional annotation of conserved genes

Celebrating the 100th anniversary of the publication of the first textbook on genetics titled "The Mechanism of Mendelian Heredity" by...

Highlight: Flies in biomedical research review is highlighted on the cover of Genetics

The March 2015 issue of Genetics highlights our perspective article that discusses the role of fruit flies in biomedical sciences.

Perspective Article: Fruit flies in biomedical research

We review the literature to identify examples of Drosophila research that made a large clinical impact, and argue that flies will...

A Drosophila genetic resource of mutants to study human genetic diseases

By generating >30,000 mutant lines, screening for phenotypes that are relevant for the development, physiology and maintenance of the...

Large-scale identification of chemically induced mutations in Drosophila melanogaster

In collaboration with Dr. Rui Chen at the Human Genome Sequencing Center at BCM, we utilized next-generation sequencing to identify...

Book Chapter: An introduction to Notch signaling

In the first chapter of the book "Notch Signaling -Methods and Protocols", we provide a general overview of Notch signaling, an...